SODIUM GUAIAZULENE SULFONATE
Sodium gualenate
CAS: 6223-35-4
Molecular Formula: C15H17NaO3S
SODIUM GUAIAZULENE SULFONATE - Names and Identifiers
SODIUM GUAIAZULENE SULFONATE - Physico-chemical Properties
| Molecular Formula | C15H17NaO3S |
| Molar Mass | 300.35 |
| Melting Point | 98°C(lit.) |
| Storage Condition | Room Temprature |
| Physical and Chemical Properties | Bioactive Sodium gualenate (Guaiazulenesulfonate sodium) is a hydrophilic derivative of cinnamene, which has excellent anti-inflammatory and callus effects. It is mainly used to study duodenal ulcer, gastric ulcer and gastritis. |
| Use | Application of sodium sulfonate is the effective ingredient of chamomile flowers, has a strong anti-pepsin, anti-inflammatory, antibacterial, anti-allergic, promote the role of mucosal metabolism, mechanism: it inhibits histamine release from inflammatory cells by local direct action; Increases the synthesis of prostaglandin E2 in mucosa, promotes granulation and epithelial cell regeneration; And reduces the activity of pepsin. |
SODIUM GUAIAZULENE SULFONATE - Nature
| melting point | 98°C(lit.) |
| storage conditions | Inert atmosphere,Room Temperature |
| Merck | 14,4554 |
Last Update：2024-04-10 22:29:15
SODIUM GUAIAZULENE SULFONATE - Security information
| RTECS number | CO4826000 |
Last Update：2024-04-10 22:29:15
SODIUM GUAIAZULENE SULFONATE - Uses and synthesis methods
overview
Sodium azulene sulfonate is chemically unstable. It will decompose under light, air oxidation and high temperature environment, and it is easy to remove sulfonic acid groups. According to existing reports, it is common for sodium azulene to contain half or one crystal water.
in vitro study
Sodium gualenate is an unstable compound, which is gradually decomposed in the solid state at room temperature. When heated, Sodium gualenate decomposes almost completely within 1 week. It was found that a kneaded mixture of Sodium gualenate and cornstarch (weight ratio; 1:250) for tableting with water is stable. So, during production, Sodium gualenate could be stabilized using water. Sodium gualenate slightly inhibits the histamine release from rat peritoneal mast cells and strongly inhibits the leukocyte emigration induced by fMLP.
in vivo studies
Sodium gualenate has been frequently used for the treatment of human gastritis. Cytoprotection is defined as the main mechanism of Sodium gualenate to protect the mucosa of the stomach and the antipeptic actions in vivo have also been shown.
Last Update：2024-04-09 19:04:55
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Product Name: Sodium gualenate Visit Supplier Webpage Request for quotationCAS: 6223-35-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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